HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Bis(trifluoromethyl)benzyl bromide → 1-[3,5-Bis(trifluoromethyl)benzyl]-5-ethyl-6-(3,5-dimethyl-phenyl)thio-2,4-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Bis(trifluoromethyl)benzyl bromide | HCID 122573 | — |
| Reactant | 6-(3,5-dimethylphenyl)sulfanyl-5-ethyl-1H-pyrimidine-2,4-dione | HCID 10492727 | — |
| Product | 1-[3,5-Bis(trifluoromethyl)benzyl]-5-ethyl-6-(3,5-dimethyl-phenyl)thio-2,4-pyrimidinedione | HCID 15957742 | 45% |
Reaction Steps
5-Ethyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 3,5-bis(trifluoromethyl)benzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (226 mg, yield: 45.0%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06987114B1 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-07ddda38b5a84ddfa44f29d6b4e70a07 |
| Source note | uspto-grants-2006_01 |