HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-1,4-difluorobenzene → 1-(2,5-Difluorobenzyl)-5-ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-1,4-difluorobenzene | HCID 522830 | — |
| Reactant | 5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione | HCID 10923266 | — |
| Product | 1-(2,5-Difluorobenzyl)-5-ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione | HCID 15957749 | 47.9% |
Reaction Steps
5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 2,5-difluorobenzyl bromide were reacted by the same way with the example 1 to obtain the titled compound (185 mg, yield: 47.9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06987114B1 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-e1f4e1b09ae64349b3cbcaedc2d1f8c9 |
| Source note | uspto-grants-2006_01 |