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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611354Generated: November 4, 2026

Picolyl chloride → 1-(Pyridin-2-ylmethyl)-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPicolyl chlorideHCID 23393—
Reactant5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 10493727—
Product1-(Pyridin-2-ylmethyl)-5-isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedioneHCID 1595778629.4%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 2-picolyl chloride were reacted by the same way with the example 1 to obtain the titled compound (112 mg, yield: 29.4%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-10625dc6889c4e66b0ab790304115ecb
Source noteuspto-grants-2006_01