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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611358Generated: November 2, 2026

3-(Chloromethyl)pyridine → 6-(3,5-Dimethylphenyl)sulfanyl-5-ethyl-1-(3-pyridylmethyl)pyrimidine-2,4-dione

https://huagongshe.com/reaction/1611358

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)pyridineHCID 18358—
Reactant6-(3,5-dimethylphenyl)sulfanyl-5-ethyl-1H-pyrimidine-2,4-dioneHCID 10492727—
Product6-(3,5-Dimethylphenyl)sulfanyl-5-ethyl-1-(3-pyridylmethyl)pyrimidine-2,4-dioneHCID 1595778925.9%

Reaction Steps

5-Ethyl-6-(3,5-dimethylphenyl)thio-2,4-pyrimidinedione and 3-picolyl chloride were reacted by the same way with the example 1 to obtain the titled compound (95 mg, yield: 25.9%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-02d27af360654423a6db318140a3de55
Source noteuspto-grants-2006_01