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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611374Generated: October 27, 2026

1-(Chloromethyl)-1H-benzotriazole → 1-(1H-benzotriazol-1-ylmethyl)-5-ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611374

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Chloromethyl)-1H-benzotriazoleHCID 3328222—
Reactant5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 10923266—
Product1-(1H-benzotriazol-1-ylmethyl)-5-ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 1595781228.6%

Reaction Steps

5-Ethyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 1-chloromethyl-1H-benzotriazole were reacted by the same way with the example 1 to obtain the titled compound (112 mg, yield: 28.6%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-ca05d954af8f40d7bd7d28b39a2cb090
Source noteuspto-grants-2006_01