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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611375Generated: October 27, 2026

1-(Chloromethyl)-1H-benzotriazole → 1-(Benzotriazol-1-ylmethyl)-6-(3,5-dimethylphenoxy)-5-isopropyl-pyrimidine-2,4-dione

https://huagongshe.com/reaction/1611375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Chloromethyl)-1H-benzotriazoleHCID 3328222—
Reactant5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 22256578—
Product1-(Benzotriazol-1-ylmethyl)-6-(3,5-dimethylphenoxy)-5-isopropyl-pyrimidine-2,4-dioneHCID 1595781326.6%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 1-chloromethyl-1H-benzotriazole were reacted by the same way with the example 1 to obtain the titled compound (108 mg, yield: 26.6%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-ecace5818b574cc48e68e250097f8acc
Source noteuspto-grants-2006_01