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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611385Generated: October 31, 2026

Methyl 2-(Bromomethyl)-3-Furoate → 1-(3-Methoxycarbonyl-2-furanylmethyl)-5-isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611385

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(Bromomethyl)-3-FuroateHCID 2736827—
Reactant5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 22256578—
Product1-(3-Methoxycarbonyl-2-furanylmethyl)-5-isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedioneHCID 1595782233.5%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 2-bromomethyl-3-methoxycarbonylfurane were reacted by the same way with the example 1 to obtain the titled compound (133 mg, yield: 33.5%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-d07b54044b5f44c8b285ee18e7de2bce
Source noteuspto-grants-2006_01