Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611387Generated: November 2, 2026

Methyl 2-(Bromomethyl)-3-Furoate → 1-(3-Methoxycarbonyl-2-furanylmethyl)-5-isopropyl-6-(3,5-dimethyl-benzoyl)-2,4-pyrimidinedione

https://huagongshe.com/reaction/1611387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(Bromomethyl)-3-FuroateHCID 2736827—
Reactant6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dioneHCID 22256582—
Product1-(3-Methoxycarbonyl-2-furanylmethyl)-5-isopropyl-6-(3,5-dimethyl-benzoyl)-2,4-pyrimidinedioneHCID 1595782439.7%

Reaction Steps

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 2-bromomethyl-3-methoxycarbonylfurane were reacted by the same way with the example 1 to obtain the titled compound (162 mg, yield: 39.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06987114B1
Source datasetuspto-grants-2006_01
ORD IDord-5c428f22f4d24f41a241c41fc4509326
Source noteuspto-grants-2006_01