1-Bromo-2-butanone → HCID 15957830, compound

HRID 1611393Notes

Reaction equation

HRID 1611393 reaction equation
[CH:1]([C:4]1[C:5](=[O:20])[NH:6][C:7](=[O:19])[NH:8][C:9]=1[O:10][C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].Br[CH2:22][C:23](=[O:26])[CH2:24][CH3:25]>>[CH2:22]([N:8]1[C:9]([O:10][C:11]2[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=2)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:20])[NH:6][C:7]1=[O:19])[C:23](=[O:26])[CH2:24][CH3:25]

Participants

3

Procedure

5-Isopropyl-6-(3,5-dimethylphenoxy)-2,4-pyrimidinedione and 1-bromo-2-butanone were reacted by the same way with the example 1 to obtain the titled compound (179 mg, yield: 49%).

Sources & evidence

ORD record
ord-c776974f30724cf9893d2deeebad71e7
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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