1-Bromo-2-butanone → HCID 15957832, compound

HRID 1611394Notes

Reaction equation

HRID 1611394 reaction equation
[CH:1]([C:4]1[C:5](=[O:21])[NH:6][C:7](=[O:20])[NH:8][C:9]=1[C:10](=[O:19])[C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].Br[CH2:23][C:24](=[O:27])[CH2:25][CH3:26]>>[CH2:23]([N:8]1[C:9]([C:10](=[O:19])[C:11]2[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=2)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:21])[NH:6][C:7]1=[O:20])[C:24](=[O:27])[CH2:25][CH3:26]

Participants

3

Reactant 2

HCID 131561-Bromo-2-butanoneHCID 222565826-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione

Product 1

HCID 15957832HCID 15957832, compoundYield 55%

Procedure

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 1-bromo-2-butanone were reacted by the same way with the example 1 to obtain the titled compound (196 mg, yield: 55%).

Sources & evidence

ORD record
ord-55d4d78408a642a99cf8d726ae7aa8b7
Source dataset
uspto-grants-2006_01
Patent number
US06987114B1

Reaction notes

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