反应详情

To a solution of 1,5-dibromopentane (23.2 g, 101 mmol), ethanol (40 mL) and water (40 mL) was dropwise added a solution of sodium sulfite (4.24 g, 33.6 mmol) in water (15 mL) under heating under reflux over 2 hr. After heating under reflux for 2 hr, the solvent was distilled away under reduced pressure and n-hexane/ethanol was added. The precipitated crystals were washed with n-hexane and dried in vacuo to give the title compound (3.81 g, 45%).

1. temperatureunder heating
2. temperatureunder reflux over 2 hr
3. temperatureAfter heating
4. temperatureunder reflux for 2 hr
5. distillationthe solvent was distilled away under reduced pressure and n-hexane/ethanol
6. additionwas added
7. washThe precipitated crystals were washed with n-hexane
8. customdried in vacuo