Ammonia → HCID 10430315, compound

HRID 1611688Notes

Reaction equation

HRID 1611688 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[C:7]2[OH:12].[OH:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][CH:23]=1)[C:17](OC)=O.[NH3:24]>>[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[C:7]2[O:12][CH2:4][CH2:5][CH2:6][CH:7]([CH3:8])[O:13][C:14]1[CH:23]=[CH:22][CH:21]=[C:16]2[C:15]=1[N:24]=[C:2]([NH2:1])[CH:3]=[CH:17]2

Participants

4

Reactant 3

HCID 222AmmoniaHCID 657465-Amino-1-naphtholHCID 88068Methyl 3-Hydroxybenzoate

Product 1

HCID 10430315HCID 10430315, compound

Procedure

The title compound was prepared according to the procedure described in Example 92 substituting 5-amino-1-naphthol for methyl 3-hydroxybenzoate. 1H NMR (500 MHz, DMSO-d6) δ ppm 8.36 (d, 1H), 7.56 (d, 1H), 7.48 (m, 2H), 7.39 (m, 2H), 7.27 (t, 1H), 7.17 (m, 1H), 7.12 (d, 1H), 6.87 (d, 1H), 6.80 (d, 1H), 4.92 (m, 1H), 4.17 (m, 2H), 2.04 (m, 4H), 1.45 (d, 3H); MS (DCI/NH3) m/z 388 [M+H]+.

Sources & evidence

ORD record
ord-a0fc0c74dcec4cbb848a2506034aabb0
Source dataset
uspto-grants-2006_01
Patent number
US06989392B2

Reaction notes

Loading…