Ammonia → 8-(4-(3-Anilinophenoxy)-1-methylbutoxy)quinolin-2-amine

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 92 substituting 3-anilinophenol for methyl 3-hydroxybenzoate. 1H NMR (500 MHz, CDCl3) δ ppm 7.91 (d, 1H), 7.26 (m, 3H), 7.16 (m, 1H), 7.12 (m, 1H), 7.07 (m, 3H), 6.94 (d, 1H), 6.91 (m, 1H), 6.60 (m, 1H), 6.52 (t, 1H), 6.37 (m, 1H), 4.69 (m, 1H), 4.03 (m, 1H), 3.96 (m, 1H), 2.18 (m, 1H), 1.96 (m, 3H), 1.46 (d, 3H); MS (DCI/NH3) m/z 414 [M+H]+.

Provenance & Evidence