Ammonia → HCID 10068862, compound

HRID 1611693Notes

Reaction equation

HRID 1611693 reaction equation
[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[OH:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][CH:23]=1)[C:17](OC)=O.[NH3:24]>>[N:1]1([C:6]2[CH:11]=[CH:10][C:9]([O:12][CH2:8][CH2:7][CH2:6][CH:11]([CH3:10])[O:13][C:14]3[CH:23]=[CH:22][CH:21]=[C:16]4[C:15]=3[N:24]=[C:5]([NH2:1])[CH:4]=[CH:17]4)=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 823151-(p-Hydroxyphenyl)imidazoleHCID 88068Methyl 3-Hydroxybenzoate

Product 1

HCID 10068862HCID 10068862, compound

Procedure

The title compound was prepared according to the procedure described in Example 92 substituting 4-(1H-imidazol-1-yl)phenol for methyl 3-hydroxybenzoate. 1H NMR (500 MHz, CDCl3) δ ppm 8.89 (s, 1H), 7.93 (d, 1H), 7.45 (s, 1H), 7.38 (s, 1H), 7.32 (m, 3H), 7.20 (dd, 1H), 7.12 (d, 1H), 7.06 (d, 1H), 6.96 (m, 2H), 4.69 (m, 1H), 4.21 (m, 1H), 4.10 (m, 1H), 2.23 (m, 1H), 2.12 (m, 1H), 1.94 (m, 2H), 1.48 (d, 3H); MS (DCI/NH3) m/z 389 [M+H]+.

Sources & evidence

ORD record
ord-f1ed3c50990f42438b796debcf188ce3
Source dataset
uspto-grants-2006_01
Patent number
US06989392B2

Reaction notes

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