Cyanoacetamide → HCID 178510529, compound

HRID 1611735Notes

Reaction equation

HRID 1611735 reaction equation
[C:1]([CH2:3][C:4](N)=O)#N.[OH:7][C:8]1[C:12]([C:13]#[N:14])=[C:11]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[S:10][N:9]=1>>[OH:7][C:8]1[C:12]([C:13]#[N:14])=[C:11]([NH:15][C:16]2[CH:17]=[CH:18][C:19]([CH:1]=[CH:3][C:4]3[CH:20]=[CH:21][CH:16]=[CH:17][CH:18]=3)=[CH:20][CH:21]=2)[S:10][N:9]=1

Participants

3

Reactant 2

HCID 7898CyanoacetamideHCID 178510528HCID 178510528, compound

Product 1

HCID 178510529HCID 178510529, compound

Procedure

The title compound was prepared from 1-isothiacyanato-4-styryl-benzene and 2-cyanoacetamide by the procedure analogous to Method 2 for 3-Hydroxy-5-phenylamino-isothiazol-4-carbonitrile. 1H NMR (300 MHz, DMSO-d6) δ: 7.22–7.65 (m, 11H). MS (ES, m/z): 320.3, [M-H]+, 318.1 [M-H]−.

Sources & evidence

ORD record
ord-ec934184aa234660893c0b236b21cec5
Source dataset
uspto-grants-2006_01
Patent number
US06989451B2

Reaction notes

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