Cyanoacetamide → HCID 178439214, compound

HRID 1611737Notes

Reaction equation

HRID 1611737 reaction equation
[C:1]([CH2:3][C:4](N)=O)#N.[OH:7][C:8]1[C:12]([C:13]#[N:14])=[C:11]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[S:10][N:9]=1>>[OH:7][C:8]1[C:12]([C:13]#[N:14])=[C:11]([NH:15][C:16]2[CH:17]=[CH:18][C:19]([CH:3]([CH3:4])[CH3:1])=[CH:20][CH:21]=2)[S:10][N:9]=1

Participants

3

Reactant 2

HCID 7898CyanoacetamideHCID 178510528HCID 178510528, compound

Product 1

HCID 178439214HCID 178439214, compound

Procedure

The title compound was prepared from 1-isothiacyanato-4-isopropyl-benzene and 2-cyanoacetamide by the procedure analogous to Method 2 for 3-Hydroxy-5-phenylamino-isothiazol-4-carbonitrile. 1H NMR (CD3OD) δ: 7.2–7.4 (m, 4H); 2.9 (q, 1H); 1.24 (d, 6H); MS (ES, m/z): 259.8, [M-H]+, 258.3 [M-H]−.

Sources & evidence

ORD record
ord-3b733bae70854912a066291883708300
Source dataset
uspto-grants-2006_01
Patent number
US06989451B2

Reaction notes

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