HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-{[(2-Methoxy-ethyl)-methyl-amino]-methyl}-N-(4-methoxy-7-phenyl-benzooxazol-2-yl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Methoxy-7-phenyl-benzooxazol-2-ylamine | HCID 22252231 | — |
| Reactant | 4-{[(2-Methoxy-ethyl)-methyl-amino]-methyl}-benzoyl chloride | HCID 22252241 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-{[(2-Methoxy-ethyl)-methyl-amino]-methyl}-N-(4-methoxy-7-phenyl-benzooxazol-2-yl)-benzamide | HCID 10366234 | — |
Reaction Steps
From 4-methoxy-7-phenyl-benzooxazol-2-yl-amine with 4-{[(2-methoxy-ethyl)-methyl-amino]-methyl}-benzoyl chloride, triethylamine and N,N-dimethyl-4-aminopyridine in THF. ES-MS m/e (%): 446 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992083B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-e165d822e4d44a2296266f131cb0d67f |
| Source note | uspto-grants-2006_01 |