HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → N-[7-(4-Fluoro-phenyl)-4-methoxy-benzooxazol-2-yl]-2-methoxymethyl-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Chloromethyl-N-[7-(4-fluoro-phenyl)-4-methoxy-benzooxazol-2-yl]-isonicotinamide | HCID 10093068 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-[7-(4-Fluoro-phenyl)-4-methoxy-benzooxazol-2-yl]-2-methoxymethyl-isonicotinamide | HCID 10319211 | — |
Reaction Steps
From 2-chloromethyl-N-[7-(4-fluoro-phenyl)-4-methoxy-benzooxazol-2-yl]-isonicotinamide with sodium hydride and ethanol in dioxane and DMF. ES-MS m/e (%): 408 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992083B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-257488e6c55f462ea69742a3b711f9b1 |
| Source note | uspto-grants-2006_01 |