Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1611973Generated: October 31, 2026

2-chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl chloride → 2-{6-[(2-Chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl)-amino]-5-ethoxy-pyridin-3-yl}-2-hydroxy-propionic acid ethyl ester

https://huagongshe.com/reaction/1611973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl chlorideHCID 22252701—
Reactant2-(6-Amino-5-ethoxy-pyridin-3-yl)-2-hydroxy-propionic acid ethyl esterHCID 23593811—
Product2-{6-[(2-Chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl)-amino]-5-ethoxy-pyridin-3-yl}-2-hydroxy-propionic acid ethyl esterHCID 69546362—

Reaction Steps

The title compound was prepared from 2-chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl chloride and 2-(6-amino-5-ethoxy-pyridin-3-yl)-2-hydroxy-propionic acid ethyl ester in a manner analogous to that described hereinabove in Example 2 using appropriate starting materials. LC/MS+=438.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06992092B2
Source datasetuspto-grants-2006_01
ORD IDord-c38d6b17cacc4351bbcb71cbd11c51bd
Source noteuspto-grants-2006_01