反应详情

7 g of the compound obtained in Step A are stirred at room temperature for 72 hours in a mixture of 100 ml of ethanol and 100 ml of 1M aqueous sodium hydroxide solution. Having been rendered acidic by 100 ml of 1M hydrochloric acid, the reaction mixture is extracted with dichloromethane. The organic fractions are dried over sodium sulphate and evaporated under reduced pressure, enabling the expected product to be isolated.

1. extractionthe reaction mixture is extracted with dichloromethane
2. dry with materialThe organic fractions are dried over sodium sulphate
3. customevaporated under reduced pressure
4. customto be isolated