HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22252356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Borane | HCID 6331 | — |
| Reactant | HCID 22252348 | HCID 22252348 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22252356 | HCID 22252356 | — |
Reaction Steps
10 ml of a 1M solution of borane in tetrahydrofuran are added to 0.4 g of the compound obtained in Example 35 in solution, under argon, in 50 ml of tetrahydroftiran and the mixture is refluxed for 8 hours. After hydrolysis with 2 ml of 4N hydrochloric acid, evaporation to dryness and conversion to the base, the hydrochloride is prepared using an ethanolic hydrogen chloride solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992085B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-0e3d3c17c6094943aabe40be91efc42c |
| Source note | uspto-grants-2006_01 |