HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylonitrile → (Octahydro-2H-pyrido[1,2-a]pyrazin-2-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | (+-)-1,4-Diazabicyclo[4.4.0]decane | HCID 2876391 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (Octahydro-2H-pyrido[1,2-a]pyrazin-2-yl)acetonitrile | HCID 22252394 | — |
Reaction Steps
8 g of octahydro-2H-pyrido[1,2-a]pyrazine and 12 ml of acrylonitrile are refluxed for 48 hours in 150 ml of acetonitrile. The solvent is then removed in vacuo to yield 11 g of a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992085B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-2c99c4fb7b024d72afe317b09907e434 |
| Source note | uspto-grants-2006_01 |