1,2-Dibromoethane → 4-(2-Bromoethoxy)benzonitrile
Reaction equation
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[Br:10][CH2:11][CH2:12]Br>>[Br:10][CH2:11][CH2:12][O:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1Participants
3
Procedure
The procedure is as for Example 53, Step A, using as substrate 4-hydroxybenzonitrile and 1,2-dibromoethane.
Sources & evidence
- ORD record
- ord-33cd66f47b3f4c8595aeddc19635133e
- Source dataset
- uspto-grants-2006_01
- Patent number
- US06992085B2
Reaction notes
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