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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612236Generated: November 1, 2026

6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine → cis-2-ethyl-6-methoxy-2,3-dihydro-1H-inden-1-amine

https://huagongshe.com/reaction/1612236

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amineHCID 22147391—
Reactant2-ethyl-6-methoxy-2,3-dihydro-1H-inden-1-one oximeHCID 73867080—
Productcis-2-ethyl-6-methoxy-2,3-dihydro-1H-inden-1-amineHCID 68811220—

Reaction Steps

Following the procedure for the preparation of 6,7-dihydro-5H-cyclopenta[b]pyridin-5-amine but substituting 2-ethyl-6-methoxy-2,3-dihydro-1H-inden-1-one oxime and making non-critical variations provided the title compound as a oil: 1H NMR (CDCl3) δ 1.03, 1.39, 2.30, 2.63, 2.86, 3.82, 4.26, 6.77, 7.12;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06992087B2
Source datasetuspto-grants-2006_01
ORD IDord-45cc39577be948be9e5fa7a9f592f791
Source noteuspto-grants-2006_01