HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl [(7-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetate--hydrogen chloride (1/1) → 121524-08-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl [(7-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetate--hydrogen chloride (1/1) | HCID 121888 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 121524-08-1 | HCID 3035442 | — |
Reaction Steps
Polymorphic SR58611 hydrochloride (95.2 g) is suspended at 70° C. in 0.3 liter of propan-2-ol. After maintaining for 12 h 30 under isothermal conditions, the suspension is composed of SR58611 hydrochloride, B form, >98%. IR spectrum and X-ray diffraction are in agreement.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992211B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-2f7a7d02f4604c47893eb6d2d6db0ecf |
| Source note | uspto-grants-2006_01 |