HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-(4-Bromo-3-oxobutyl)-1H-isoindole-1,3(2H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-(3-Oxobutyl)isoindoline-1,3-dione | HCID 290728 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-Bromo-3-oxobutyl)-1H-isoindole-1,3(2H)-dione | HCID 3759744 | — |
Reaction Steps
To a suspension of 130 g (0.6 mole) of 4-phthalimido butan-2-one (7a) in 1000 ml of absolute methanol is added 96 g (0.6 mole) of bromine and the reaction mixture is stirred for 24 hours at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05190589 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-8676e1e96ec84919bf2d9781e97b28ca |
| Source note | uspto-grants-1993_03 |