Formaldehyde → HCID 178440781, compound

HRID 1612592Notes

Reaction equation

HRID 1612592 reaction equation
[SH:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[C:7]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:12]=1[OH:21])([CH3:10])([CH3:9])[CH3:8].C=O.[CH2:24](NCCCC)CCC>C(O)C>[C:17]([C:13]1[CH:14]=[C:15]([CH:16]=[C:11]([C:7]([CH3:10])([CH3:9])[CH3:8])[C:12]=1[OH:21])[CH2:24][C:5]1[NH:4][N:3]=[C:2]([SH:1])[N:6]=1)([CH3:20])([CH3:19])[CH3:18]

Participants

6

Reactant 4

HCID 712FormaldehydeHCID 8148DibutylamineHCID 314052,6-Di-tert-butylphenolHCID 178527894HCID 178527894, compound

Product 1

HCID 178440781HCID 178440781, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3-Mercapto-1,2,4-triazole (20.2 g, 0.2 mol), 2,6-di-tertbutylphenol (41.2 g, 0.2 mol), paraformaldehyde (6.0 g, 0.2M) and di-n-butylamine (2 ml) are heated, under reflux, in ethanol (100 ml) for ten hours. The reaction mixture is cooled, and the product is crystallised as a white solid (43 g, 67% of theory) having a m.p. of 184°-185° C. (Found C=63.39; H=8.03; N=13.29; S=10.20 C17H25N3OS requires C=63.95; H=7.84; N=13.17 and S=10.03%).

Workup

  1. temperatureThe reaction mixture is cooled
  2. customthe product is crystallised as a white solid (43 g, 67% of theory)

Sources & evidence

ORD record
ord-aec61dd8d28043de9e538ff8a4ab5a0d
Source dataset
uspto-grants-1993_03
Patent number
US05190723

Reaction notes

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