Dimethyl Sulfoxide → 1-(2-Chlorobenzyl)-2-methylbenzimidazole-6-acetonitrile

HRID 161265Notes

Reaction equation

HRID 161265 reaction equation
[CH3:43][S:44]([CH3:45])=[O:46].[Cl:23][c:24]1[c:25]([CH2:26][n:27]2[c:28]([CH3:38])[n:29][c:30]3[c:31]2[cH:32][c:33]([CH2:36][Cl:37])[cH:34][cH:35]3)[cH:39][cH:40][cH:41][cH:42]1.[K:1][O:2][C:3]#[N:4].[O:5]1[CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][O:20][CH2:21][CH2:22]1>>[C:3](#[N:4])[CH2:36][c:33]1[cH:32][c:31]2[n:27]([CH2:26][c:25]3[c:24]([Cl:23])[cH:42][cH:41][cH:40][cH:39]3)[c:28]([CH3:38])[n:29][c:30]2[cH:35][cH:34]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 2855718-Crown-6HCID 226203421h-Benzimidazole,6-(chloromethyl)-1-[(2-chlorophenyl)methyl]-2-methyl-HCID 178418250HCID 178418250, compound

Product 1

HCID 186809811-(2-Chlorobenzyl)-2-methylbenzimidazole-6-acetonitrile

Sources & evidence

ORD record
ord-6160568a98dc4f409e9453a1e467cac5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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