Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 10263800 | HCID 10263800 | — |
| Product | HCID 10037816 | HCID 10037816 | — |
Reaction Steps
A mixture of 1.4 g (5.8 mMol) of ethyl 3-aminopropyl(1,1-difluorobutyl)phosphinate and 15 ml of 12M hydrochloric acid is stirred for 8 hours at 80° C. The reaction mixture is evaporated to dryness and the residue is recrystallized from ethanol/ether giving 3-aminopropyl-(1,1-difluorobutyl)phosphinic acid hydrochloride, m.p. 149°-151° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05190933 |
|---|
| Source dataset | uspto-grants-1993_03 |
|---|
| ORD ID | ord-bd21b70a71614d6a925863cc8fd087b5 |
|---|
| Source note | uspto-grants-1993_03 |
|---|
