Methane → 2-Amino-6-methylpyridin-3-ol

HRID 1612787Notes

Reaction equation

HRID 1612787 reaction equation
[N+:1]([C:4]1[C:9]([OH:10])=[CH:8][CH:7]=[C:6]([CH3:11])[N:5]=1)([O-])=O.C>CO>[NH2:1][C:4]1[C:9]([OH:10])=[CH:8][CH:7]=[C:6]([CH3:11])[N:5]=1

Participants

4

Reactant 2

HCID 297MethaneHCID 848016-Methyl-2-nitropyridin-3-ol

Product 1

HCID 885002-Amino-6-methylpyridin-3-ol

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3.5 g of 2-nitro-3-hydroxy-6-methylpyridine are placed under a hydrogen pressure in 50 ml of methanol in the presence of 1 gram of palladinized charcoal. The mixture is stirred and filtered. The methanol is evaporated off.

Workup

  1. filtrationfiltered
  2. customThe methanol is evaporated off

Sources & evidence

ORD record
ord-c5e9cefedd2247979678b93298fa06e8
Source dataset
uspto-grants-1993_03
Patent number
US05190960

Reaction notes

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