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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612847Generated: November 3, 2026

Phenyl-2-thienylmethyl chloride → 4-(Phenyl-2-thienylmethoxy)-1-[3-(2-nitrophenoxy)-3-methylpropyl]piperidine

https://huagongshe.com/reaction/1612847

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl-2-thienylmethyl chlorideHCID 10512583—
Reactant4-Hydroxy-1-[3-methyl-3-(2-nitrophenoxy)propyl]piperidineHCID 19776715—
Reactant4-Hydroxy-1-[3-(2-nitrophenoxy)propyl]piperidineHCID 19776793—
Product4-(Phenyl-2-thienylmethoxy)-1-[3-(2-nitrophenoxy)-3-methylpropyl]piperidineHCID 19776813—

Reaction Steps

The procedure of Example 36 (a) was repeated except for using phenyl-2-thienylmethyl chloride and 4-hydroxy-1-[3-methyl-3-(2-nitrophenoxy)propyl]piperidine instead of phenyl-2-thienylmethyl chloride and 4-hydroxy-1-[3-(2-nitrophenoxy)propyl]piperidine to give oily 4-(phenyl-2-thienylmethoxy)-1-[3-(2-nitrophenoxy)-3-methylpropyl]piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05190959
Source datasetuspto-grants-1993_03
ORD IDord-8adb53932d094f3faceb00ba667ba1aa
Source noteuspto-grants-1993_03