反应详情

13.5 kg L-carnitine nitrile chloride was dissolved in 22 liters concentrated hydrochloric acid and hydrolyzed to L-carnitine chloride, as described in Example 2. It was subsequently reacted to betaine in the highly basic ion exchanger (Amberlite IRA-416). After appropriate reprocessing, 11.1 kg colorless L-carnitine with (α)D20 =-30.8° and an HPLC concentration of 99.7% was isolated.