HCID 19777265, compound → 2-(Ethoxymethyl)morpholine

HRID 1612959Notes

Reaction equation

HRID 1612959 reaction equation
C([N:8]1[CH2:13][CH2:12][O:11][CH:10]([CH2:14][O:15][CH2:16][CH3:17])[CH2:9]1)C1C=CC=CC=1>[C].[Pd].C(O)C>[CH2:16]([O:15][CH2:14][CH:10]1[O:11][CH2:12][CH2:13][NH:8][CH2:9]1)[CH3:17]

Participants

4

Reactant 1

HCID 19777265HCID 19777265, compound

Product 1

HCID 197772592-(Ethoxymethyl)morpholineYield 70.9%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

4-Benzyl-2-ethoxymethylmorpholine (1.6 g) and 10% palladium-carbon (200 mg) are added to ethanol (30 ml), and the mixture is stirred under hydrogen pressure of 5 kg/cm2 for 24 hours. Palladium-carbon is filtered off, and the solvent is distilled off under reduced pressure to give the title compound (0.7 g) as colorless liquid.

Workup

  1. filtrationPalladium-carbon is filtered off
  2. distillationthe solvent is distilled off under reduced pressure

Sources & evidence

ORD record
ord-05839dc1ea714cb08a852c0cb9bc949f
Source dataset
uspto-grants-1993_03
Patent number
US05191079

Reaction notes

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