HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-[6-[2,3-Bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 3-Hydroxybenzoate | HCID 88068 | — |
| Reactant | 1-(6-Iodohexyl)-2,3-bis(phenylmethoxy)benzene | HCID 14986285 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-[6-[2,3-Bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid methyl ester | HCID 14986346 | 66% |
Reaction Steps
A mixture of 0.58 g of 1-(6-iodohexyl)-2,3-bis (phenylmethoxy)benzene, 0.18 g of 3-hydroxybenzoic acid methyl ester and 0.25 g of potassium carbonate in 15 mL of acetone was stirred at reflux for 18 hours. Workup as in Example 16 and purification by HPLC using toluene gave 0.40 g (66% yield) of 3-[6-[2,3-bis(phenylmethoxy)phenyl]hexyloxy]benzoic acid methyl ester as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05191108 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-f3ae2a24b7e94cc19dc719bf3c7d7361 |
| Source note | uspto-grants-1993_03 |