反应详情

25 g of 1-phenyl-3-anilino-2-pyrazoline-5-one, 180 g of ethyl acetoacetate, and 150 ml of acetic acid were heated while refluxing for 6 hours. The reaction solution was diluted with water, and the solid formed was crystallized from acetonitrile to obtain 10.9 g of 2,7-diphenyl-4-methylpyrazolo[3,4-b]pyridine-3,6-dione. Melting point: 145° to 147° C.

1. temperaturewhile refluxing for 6 hours
2. customthe solid formed
3. customwas crystallized from acetonitrile