Hydrochloric Acid → HCID 19775313, compound

Participants

Reaction Steps

The free base of the title compound was prepared similarly to the procedure of Example 40 using 1-diphenylmethoxy-2-[N-(4-ethoxycarbonylbenzyl)-N- methylamino]-2-methylpropane (see Example 28) and lithium aluminium hydride. The resulting oil was dissolved in ether and the solution treated with an excess of saturated ethereal hydrogen chloride. The resulting precipitated oil was collected, washed with ether and dried to give the title compound as a colourless foam which was characterised as a hydrochloride containing 0.25 molar equivalents of water (377 mg, 38%).

Provenance & Evidence