HCID 19775561, compound → HCID 19775564, compound

Participants

Reaction Steps

4.7 g of 2-ethoxycarbonylaminomethyl-5-(4-nitrobenzyl)-4-propylthiazole (13 mmol) in 100 ml of ethanol are hydrogenated at room temperature under 1 atmosphere in the presence of 5 g of Raney nickel. The reaction mixture is filtered and then concentrated to give 2 g of 2-ethoxycarbonylaminomethyl-5-(4-aminobenzyl)-4-propylthiazole in the form of a beige powder melting at 126° C.

Provenance & Evidence