Sodium Hydroxide → HCID 19775597, compound

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Reaction Steps

To 11.7 g of the crude hydrochloride salt from Example 10 above in 200 ml of water is added 4.0 g (0.05 mole) of 50% sodium hydroxide. The mixture is stirred for 15 minutes and then the organic soluble material is extracted into 2×200 ml of ether. The combined extracts are washed with 2×50 ml of water, dried over anhydrous magnesium sulfate, and concentrated to give 8.3 g (78.5%) of the oil product.

Provenance & Evidence