1-Bromo-3-chloropropane → HCID 67859794, compound

HRID 1613263Notes

Reaction equation

HRID 1613263 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH3:17])[CH:11]=2)=[CH:4][CH:3]=1.Br[CH2:19][CH2:20][CH2:21][Cl:22]>>[Cl:22][CH2:21][CH2:20][CH2:19][O:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH3:17])[CH:11]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 80061-Bromo-3-chloropropaneHCID 389210HCID 389210, compound

Product 1

HCID 67859794HCID 67859794, compoundYield 92%

Procedure

The procedures of Example 1 were followed using 4-hydroxy-3'-methoxystilbene (5.0 g, 22 mmol) and 1-bromo-3-chloropropane (4.5 mL, 44 mmol) to give 6.1 g (92%) of (E)-4-chloropropoxy-3'-methoxystilbene as an amber oil. 1NMR (CDCl3): δ7.51-6.74 (m,10H), 4.11 (t,2H), 3.81 (s,3H), 3.72 (t,2H), 2.22 (m,2H).

Sources & evidence

ORD record
ord-e7d61b00a159486cb9135b57780a99c4
Source dataset
uspto-grants-1993_03
Patent number
US05192786

Reaction notes

Loading…