HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 4-Acetylaminomethyl-1-ethylpyridinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | N-(4-Pyridinylmethyl)acetamide | HCID 289830 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-Acetylaminomethyl-1-ethylpyridinium iodide | HCID 19775529 | — |
Reaction Steps
A solution of 4-acetylaminomethylpyridine (22.40 g) and ethyl iodide (17.9 ml) in acetone (300 ml) was heated under reflux for 24 hours and then the solvent was evaporated in vacuo. The residue was washed with a mixture of n-hexane, ethyl acetate and ethanol to give very hygroscopic 4-acetylaminomethyl-1-ethylpyridinium iodide (42.18 g), which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05192779 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-72871ffb1d7949a193402c3c0e64480b |
| Source note | uspto-grants-1993_03 |