Iodoethane → 4-Acetylaminomethyl-1-ethylpyridinium iodide

HRID 1613289Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1613289
[C:1]([NH:4][CH2:5][C:6]1[CH:11]=[CH:10][N:9]=[CH:8][CH:7]=1)(=[O:3])[CH3:2].[CH2:12]([I:14])[CH3:13]>CC(C)=O>[I-:14].[C:1]([NH:4][CH2:5][C:6]1[CH:7]=[CH:8][N+:9]([CH2:12][CH3:13])=[CH:10][CH:11]=1)(=[O:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 6340IodoethaneHCID 289830N-(4-Pyridinylmethyl)acetamide

Produkt 1

HCID 197755294-Acetylaminomethyl-1-ethylpyridinium iodide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A solution of 4-acetylaminomethylpyridine (22.40 g) and ethyl iodide (17.9 ml) in acetone (300 ml) was heated under reflux for 24 hours and then the solvent was evaporated in vacuo. The residue was washed with a mixture of n-hexane, ethyl acetate and ethanol to give very hygroscopic 4-acetylaminomethyl-1-ethylpyridinium iodide (42.18 g), which was used without further purification.

Aufarbeitung

  1. temperatureunder reflux for 24 hours
  2. customthe solvent was evaporated in vacuo
  3. washThe residue was washed with a mixture of n-hexane, ethyl acetate and ethanol

Quellen und Nachweise

ORD-Eintrag
ord-72871ffb1d7949a193402c3c0e64480b
Quelldatensatz
uspto-grants-1993_03
Patentnummer
US05192779

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