1-(2,6-Diisopropylphenyloxy)-2-propanol → 1-(2,6-Diisopropylcyclohexyloxy)-2-propanol

Participants

Reaction Steps

The synthesis was carried out in the same manner as described in Example 3b, except that 30 g (0.13 mol) of 1-(2,6-diisopropylphenyloxy)-2-propanol were used instead of 50 g (0.23 mol) of 1-(2-tert-butylphenyloxy)-2-butanol and the amount of the same palladium catalyst was increased to 1.5 g. The reaction was carried out for 5 hours and 21 g of 1-(2,6-diisopropylcyclohexyloxy)-2-propanol were obtained in a 67% yield.

Provenance & Evidence