HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(Benzodioxan-5-yl)-1-[2-(ind-1-en-1-yl)-acetyl]-piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1H-Indene-3-acetic acid | HCID 3014022 | — |
| Reactant | 4-(Benzodioxan-5-yl)-1-[2-(ind-1-en-1-yl)-ethyl]-piperazine | HCID 10451312 | — |
| Product | 4-(Benzodioxan-5-yl)-1-[2-(ind-1-en-1-yl)-acetyl]-piperazine | HCID 11740250 | 30% |
Reaction Steps
4-(benzodioxan-5-yl)-1-[2-(ind-1-en-1-yl)-ethyl]-piperazine and its hydrochloride, m.p. (K): 254°-256° C., by reduction of 4-(benzodioxan-5-yl)-1-[2-(ind-1-en-1-yl)-acetyl]-piperazine (yield: 30%), which was itself prepared in a yield of 66% from 2-(ind-1-en-1-yl)acetic acid [m.p. (K): 92°-94° C.]and N-(benzodioxan-5-yl)piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194437 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-a0f38516ab574bf4aece3b51c8e5d7b2 |
| Source note | uspto-grants-1993_03 |