反应详情

A solution of 46.83 g (0.25 mol) of 2-(N,N-dimethylamino)ethyl 4-methylvalerate (prepared as described in Example 1) and 31.65 g (0.25 mol) of benzyl chloride in 250 ml of acetonitrile was heated at reflux for 1.25 hours. The reaction mixture was then concentrated to a viscous oil and used in the ion exchange step with no further purification.

1. temperatureat reflux for 1.25 hours
2. concentrationThe reaction mixture was then concentrated to a viscous oil
3. customused in the ion exchange step with no further purification