反应详情

To a solution of 26.33 g (0.05 mol) of N-(2-(benzoyloxy)ethyl)-N,N-dimethyl-n-octadecylammonium bromide (prepared as described in Example 36) dissolved in 500 ml of water at 70° C. was added a solution of 11.26 g (0.05 mol) of sodium m-nitrobenzenesulfonate in 100 ml of water. The resultant mixture was extracted with methylene chloride. The water layer was separated and the organic layer was dried over MgSO4 and concentrated. The solid was recrystallized from ethyl acetate, collected, washed with ligroine, and dried to yield 21.7 g of the title compound; mp=80°-3° C. ##STR26##

1. extractionThe resultant mixture was extracted with methylene chloride
2. customThe water layer was separated
3. dry with materialthe organic layer was dried over MgSO4
4. concentrationconcentrated
5. customThe solid was recrystallized from ethyl acetate
6. customcollected
7. washwashed with ligroine
8. customdried