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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1613712Generated: November 1, 2026

Ibuprofen, (+-)- → beta-Methyl-4-(2-methylpropyl)benzeneethanol

https://huagongshe.com/reaction/1613712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIbuprofen, (+-)-HCID 3672—
ReactantAluminium lithium hydrideHCID 21226445—
Productbeta-Methyl-4-(2-methylpropyl)benzeneethanolHCID 595160—

Reaction Steps

The title compound was prepared by the procedure of Preparation 2 in quantitative yield from α-methyl-4-(2-methylpropyl)benzeneacetic acid which is Ibuprofen® and lithium aluminum hydride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05194446
Source datasetuspto-grants-1993_03
ORD IDord-d9778174d4ce46b8a9bd90b934753e5e
Source noteuspto-grants-1993_03