4-Hydroxybiphenyl → [1,1'-Biphenyl]-4-yl sulfamate

HRID 1613784Notes

Reaction equation

HRID 1613784 reaction equation
[C:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[S:15]([N:18]=C=O)(=[O:17])=[O:16].C1(CC#N)C=CC=CC=1>C1(C)C=CC=CC=1>[C:7]1([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:8]=[CH:9][C:10]([O:13][S:15](=[O:17])(=[O:16])[NH2:18])=[CH:11][CH:12]=1

Participants

5

Reactant 3

HCID 71034-HydroxybiphenylHCID 8794PhenylacetonitrileHCID 70918Chlorosulfonyl isocyanate

Product 1

HCID 12411107[1,1'-Biphenyl]-4-yl sulfamateYield 69%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

This compound was prepared according to the procedure used in Example 84. A mixture of 17.0 g (0.1 mole) of 4-phenylphenol, 14.8 g (0.105 mole) of chlorosulfonyl isocyanate and 100 ml of toluene gave 17.2 g (69%) of white crystals, mp 166°-168° C. (benzene-acetonitrile).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-b495a1f6015749aa9b8bd7f062dd1213
Source dataset
uspto-grants-1993_03
Patent number
US05194446

Reaction notes

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