反应详情

Aqueous 5N hydrochloric acid (1 ml) was added to a stirred solution of (20Z)-20-formamido-3-methoxypregna-3,5,17(20)-triene-9α,21-diol (70 mg) in methanol (4 ml). The reaction mixture was stirred at room temperature for 1 hour, then extracted with ethyl acetate. The organic extract was washed with an aqueous sodium bicarbonate solution, twice with water, dried and concentrated under reduced pressure to afford the title compound.

1. extractionextracted with ethyl acetate
2. extractionThe organic extract
3. washwas washed with an aqueous sodium bicarbonate solution, twice with water
4. customdried
5. concentrationconcentrated under reduced pressure