hydroxylamine-O-sulfonic acid → HCID 19774693, compound

HRID 1614013Notes

Reaction equation

HRID 1614013 reaction equation
[CH:1]([CH:3]1[CH2:8][C:7](=[O:9])[CH:6]([C:10](=[O:12])[CH3:11])[C:5](=[O:13])[CH2:4]1)=O.[NH2:14]OS(O)(=O)=O>O>[O:13]=[C:5]1[CH:6]([C:10](=[O:12])[CH3:11])[C:7](=[O:9])[CH2:8][CH:3]([C:1]#[N:14])[CH2:4]1

Participants

4

Reactant 2

HCID 76284hydroxylamine-O-sulfonic acidHCID 15003566HCID 15003566, compound

Product 1

HCID 19774693HCID 19774693, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

19.3 g (0.11 mol) of 5-formyl-2-acetylcyclohexane-1,3-dione were introduced into 200 ml of distilled water and, at room temperature, 14.7 g (0.13 mol) of hydroxylamine-O-sulfonic acid were added. The mixture was then stirred at room temperature for 17 h. The precipitate was filtered off with suction, washed with water and dried. 11.5 g (61% of theory) of 3,5-dioxo-4-acetylcyclohexanecarbonitrile were obtained (melting point 94° to 97° C).

Workup

  1. filtrationThe precipitate was filtered off with suction
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-346a2071242e4f20a7f8b074749a79b9
Source dataset
uspto-grants-1993_03
Patent number
US05194650

Reaction notes

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