Hydrochloric Acid → HCID 19774697, compound

HRID 1614017Notes

Reaction equation

HRID 1614017 reaction equation
[O:1]=[C:2]1[CH:7]([C:8](=[O:11])[CH2:9][CH3:10])[C:6](=[O:12])[CH2:5][CH:4]([C:13]#[N:14])[CH2:3]1.[CH2:15]([SH:17])[CH3:16].[ClH:18]>C(OCC)C>[ClH:18].[O:12]=[C:6]1[CH:7]([C:8](=[O:11])[CH2:9][CH3:10])[C:2](=[O:1])[CH2:3][CH:4]([C:13]([S:17][CH2:15][CH3:16])=[NH:14])[CH2:5]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 6343EthanethiolHCID 19774688HCID 19774688, compound

Product 1

HCID 19774697HCID 19774697, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

19.3 g (0.1 mol) of 3,5-dioxo-4-propionylcyclohexanecarbonitrile and 6.5 g (0.105 mol) of ethyl mercaptan were dissolved in 800 ml of dry diethyl ether and reacted with hydrogen chloride as described in Example 2.1: 20.7 g (71% of theory) of compound 2.2 [melting point 180°-185° C. (decomposition)].

Sources & evidence

ORD record
ord-1810789b5a5745b6b16d490f047bd4f4
Source dataset
uspto-grants-1993_03
Patent number
US05194650

Reaction notes

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